- Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining (10)
- Identification and preclinical validation of metabolic bottlenecks for radiosensitization in the context of SLC25A1 inhibition. (10)
- Regional immunological effects of proton therapy on the brain (10; 20)
MILabs was founded in 2006 by Prof. Freek Beekman as a molecular imaging spin-off from the University Medical Centre Utrecht, the Netherlands. Today, the company is one of the global leaders in molecular imaging with the development of high-performance preclinical micro-PET, micro-SPECT, micro-CT, and Optical Tomography systems as well as human high-resolution SPECT. These imaging systems have received many international awards from the physics and molecular imaging community. Currently, MILabs’ imaging devices support the research of many hundreds of satisfied users worldwide at universities, CRO’s and pharmaceutical companies.
Tromp Medical is the largest independent medical imaging sales and service organization of Western Europe. They sell, install and maintain various types of medical imaging equipment from leading, highly innovative manufacturers, including Canon Medical Systems, Carestream, Hologic and Ziehm Imaging, throughout the Benelux, Nordics, France and Spain.
Tromp Medical has long-standing relations with a large client base across Western Europe with an installed base of over 5.000 medical imaging systems. Customers include university hospitals, general hospitals, private clinics, research centers and screening programs.
- Overcoming radioresistance induced by cycling hypoxia in Ewing Sarcoma by targeting metabolic adaptation mechanisms (10; 40)
- Airway stem cells from Chronic Obstructive Pulmonary Disease (COPD) patients preserve patient phenotypes and have increased radiation sensitivity. (10)
- Caffeic Acid Phenethyl Ester (CAPE), a natural radiosensitizer for lung adenocarcinomas (10)
- Defects in DNA Damage Response Machinery Pave the Avenue toward Radiation Quality-Specific Radiosensitivity of Cancer Cells (10)
- Developing modulators of tumour hypoxia through inhibition of cellular oxygen consumption (10)
- DNA-PK as a target for radiosensitization in high-risk Myc-Driven Medulloblastoma. (10)
- Genetic and metabolic control of radiotherapy-induced breast cancer metastasis (10)
- Hyperthermia-mediated BRCA2 degradation enhances proton radiosensitivity of FaDu cells (10; 20)
- Identification of a mitochondrial control of radioresistance in human breast cancer models (11)
- Impact of Ionizing Radiation on the Energy Metabolism of Normal and Tumor Cells in the Brain (10)
- Internalizing Radioimmunoconjugates to Target KRAS Cancer Cells for Simultaneous Radio-Ligand Therapy and Radiosensitization (10)
- Interplay between DNA-PKcs and Rad54 in repair of X-ray induced DNA damage (10; 20)
- Quantitative imaging of hypoxic CAIX+ areas in syngeneic mouse models (10; 20)
- Targeting Survival Kinase DYRK1B: A novel approach to overcome radiotherapy-related treatment resistance (10)
- Targeting tumor associated macrophages improves the response of subcutaneous murine head and neck tumors (MOPC) to fractionated radiotherapy in vivo (10)
- The radiobiological and dosimetric challenges to combining radiopharmaceutical and external beam radiation therapies (10)
- Single-cell analysis reveals distinct responses of salivary gland stem cells to photon and proton irradiation (10; 20)
- AsiDNA protects the normal tissue against chemo- and radio-induced toxicity (10; 20)
- POLQ inhibitors as radiosensitizers - from concept to compounds (10)
- Identification of signaling pathways driving radiation-induced adverse effects in the lung - Insight from systems analysis of radiation response networks (10)
- Targeting serine/glycine metabolism to improve radiotherapy responses in Non-Small Cell Lung Cancer (10)
